THROMBOSIS PATTERNS AND CLINICAL OUTCOME OF COVID-19 VACCINE-INDUCED IMMUNE THROMBOTIC THROMBOCYTOPENIA: A SYSTEMATIC REVIEW AND META-ANALYSIS

Thrombosis patterns and clinical outcome of COVID-19 vaccine-induced immune thrombotic thrombocytopenia: A Systematic Review and Meta-Analysis

Objectives: To meta-analyse the clinical manifestations, diagnosis, treatment, and mortality of vaccine-induced immune thrombotic thrombocytopenia (VITT) after adenoviral vector vaccination.Methods: Eighteen studies of VITT after ChAdOx1 nCoV-19 or Ad26.COV2.S vaccine administration were reviewed from PubMed, Scopus, Embase, and Web of Science.The

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THBS1+ myeloid cells expand in SLD hepatocellular carcinoma and contribute to immunosuppression and unfavorable prognosis through TREM1

Summary: Hepatocellular carcinoma (HCC) is an inflammation-associated cancer arising from viral or non-viral etiologies including steatotic liver diseases (SLDs).Expansion of immunosuppressive myeloid cells is a hallmark of inflammation and cancer, but their heterogeneity in HCC is not fully resolved and might underlie immunotherapy resistance.Here

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Infective endocarditis in the U.S., 1998-2009: a nationwide study.

BACKGROUND: Previous studies based on local case series estimated the annual incidence of endocarditis in the U.S.at about 4 per 100,000 population.Small-scale studies elsewhere have reported similar incidence rates.However, no nationally-representative population-based studies have verified these estimates.METHODS AND FINDINGS: Using the 1998-2009

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